A case of chronic granulomatous disease in which the patient survived a recurrence of suspected Aspergillus brain abscess.

Chronic granulomatous disease (CGD) is one of the congenital immunodeficiencies, which affects intracellular biocidal activity through the impairment of superoxides production. Aspergillus species are a major cause of death in CGD patients and the mortality rate of cerebral aspergillosis in immunocompromised patients is reported to be nearly 100%1). Very few reports to date have described surviving cases of cerebral aspergillosis in CGD, either with an X-linked2)3) or an autosomal recessive trait4). Moreover, no reports could be found on the recurrence of brain abscesses in CGD. Practical information in terms of the management of a given patient and of radiological characterization concerning this devastating condition is, therefore, still limited. A case of X-linked CGD is presented here which survived a recurrence of brain abscess due presumably to Aspergillus.